SHCS

Swiss HIV Cohort Study

& Swiss Mother and Child HIV Cohort Study

Ongoing Collaboration Projects

NamePI and coord.
centre
SHCS
representiatives
TopicRegion
ACHIeV2E
A collaboration on HIV-2 infection
Linda Wittkop, FranceJ. Böni (lab),
A. Calmy (clinic)
Diagnosis, natural history, and ART of HIV-2 Infection13 cohorts from Europe, Africa, North America
ATHENA, AQUITAINE, ICONA, ARCA
5 European cohort collaboration SHCS #816
Flaminia Olearo, HUGA. Calmy,
R. Kouyos
The impact of mutations on the effectiveness of abacavir/lamivudine/dolutegravir regimens prescribed in treatment-experienced patientsEurope
BEEHIVE
Bridging the evolution and epidemiology of HIV in Europe
Christoph Fraser, Oxford University, OxfordH. Günthard,
R. Kouyos
Evolution and Epidemiology of HIV in EuropeEuropean Community (UK, Netherlands, Switzerland)
Causal effect of treatment on survival from HIV/AIDSO. Aalen, Norway,
J. Sterne, Bristol Univ, UK
B. Ledergerber  
Cellular Immune Responses and Immuneactivation against HIVA. Oxenius, ETHZH. GünthardStudy cellular immune responses and activation of CD4 and CD8 cells 
Effect of TDF on HCC incidenceA. Rauch,
G. Wandeler
A. RauchAssessing the effect of HBV therapy on HCC in HIV-infected patientsEurope
EPPICC
European Pregnancy and Paediatric HIV Cohort Collaboration
 T. Klimkait  
HBV outcomes in HIV/HBV-coinfected nd HBV-monoinfected patients in SwitzerlandG. WandelerA. RauchComparison of HBV virological outcomes between HIV and HIV-uninfected individuals 
HIV CAUSAL
HIV Causal Collaboration #498
M. Hernan, Harvard School of Public Health, Boston, USAH. Bucher,
M. Egger
When to start HAART? Best initial regimen? When to switch HAART?12 cohorts from USA and Europe
ICGH
International Collaboration for the Genomics of HIV
a consortium of 25 cohorts / studies coordinated by the SHCSJ. FellayA collaborative research effort of all groups active in host genomics of HIV diseaseAmerica, Europe, Africa, Australia
IeDEA-hepatitis
Long-term hepatitis B outcomes in HIV-infected patients in southern Africa and Switzerland
G. Wandeler, ISPM BernG. Wandeler,
A. Rauch
HIV/HBV-coinfection cohortssub-Saharan Africa
Kinetics of Hepatitis B Virus markers in treated HIV/HBV-coinfected patientsG. Wandeler,
ISPM Bern
G. Wandeler,
A. Rauch
Assessing the dynamics of HBV markers in HIV/HBV coinfected patientsEurope
LoHRA
Low HBV Replication and Adherence in Long-term TDF/&ETV-treated HIV-HBV infected patients
K. Lacombe, ParisA. Rauch,
G. Wandeler
Evaluating impact of low-level HBV replication in HIV-infected patientsEurope
Mathematical modelling and spread of HIV drug resistance at the population level in the SHCSS. Bonhoeffer, ETHZ,
T. Stadler, ETHZ
H. GünthardPoplulation mathematical modelling of spread of HIV drug resistance on the population level 
Modelling hepatitis C treatment-as-preventions strategiesA. RauchA. Rauch,
L. Salazar
Evaluation treatment-as-prevention to curb the HCV epidemicsAustralia
Multi-cohort study to inform hepatocellular carcinoma screening strategies in HIV/HBV-coinfected individuals on tenofovir-containing therapyG. Wandeler,
ISPM Bern
G. Wandeler,
A. Rauch
Investigating and improving progonstic score for HCC screening in HIV-infected patientsEurope
Multiple projects in TanzaniaSwiss Tropical and Public Health Institute, BaselM. Battegay,
H. Furrer
 Tanzania
NESCent
The evolution of virulence in a human infectious disease: the case study of HIV
J. Herbeck,
V. Müller
H. GünthardHIV virulence over time in large global cohort collaborationsseveral Western European, American and most likely also African cohorts
Penta-EICG
European infant collaboration
C. Gianquinto, Fondazion Penta-Onlus, Padova, ItalyC. Rudin,
P. Paioni
Treatment of childrenseveral European
PopGen
Population kinetic modelling of metabolic traits in HIV-infected individuals
C. Czajka, University of LausanneP. TarrDevelopment of a population kinetics model to describe the dynamics and interindividual variability of metabolic traits after ART initiation 
Principals of collaboration with the National Institute for Cancer Epidemiology and Registration (NICER)R. Heusser, NICERM. EggerLinkage study with Swiss CR 
RESPOND
International Cohort Consortium on Infectious Diseases
Amanda Mocroft,
Jens Lundgren
H. Günthard,
A. Scherrer
Long term outcomes in HIIV-infected individuals: aging, comorbididies, ART etc.Europe
TB:HIV
Co-infection with mycobacterium tuberculosis among HIV patients P501 and P663
Jens Lundgren, CHIP, DKH. FurrerCo-infection with TBseveral Eastern & Western European

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