SHCS

Swiss HIV Cohort Study

& Swiss Mother and Child HIV Cohort Study

Page 27

Glass et al., Infezione HIV asintomatica e fallimento terapeutico

Le persone con infezione HIV, che non hanno segni di malattia al momento di iniziare una terapia, hanno un rischio più elevato di fallimento terapeutico?   Clinical Infectious Disease Negli ultimi anni si consiglia alle persone con infezione HIV di cominciare una terapia il più presto possibile dopo la diagnosi. Questa strategia è definita come “test […]

Bansi-Matharu et al., Contemporary antiretrovirals and body-mass index

Contemporary antiretrovirals and body-mass index: a prospective study of the RESPOND cohort consortium.   Lancet HIV Bansi-Matharu et al. on behalf of the RESPOND cohort consortium aimed to investigate factors associated with weight gain among people in the RESPOND cohort, focusing particularly on contemporary antiretrovirals, such as dolutegravir and tenofovir alafenamide. People with HIV under […]

Glass et al., Asymptomatische HIV Infektion und Behandlungsversagen

Haben Menschen mit HIV Infektion, welche zum Zeitpunkt des Therapiebeginns keine Krankheitszeichen haben, ein grösseres Risiko eines Behandlungsversagens?    Clinical Infectious Disease In den letzten Jahren hat sich durchgesetzt, dass HIV-infizierte Menschen möglichst früh nach der Diagnose behandelt werden sollten. Diese Strategie wird auch «test and treat» also «testen und behandeln» genannt. Nun stellt sich die […]

Glass et al., Infection VIH sans symptômes et échec du traitement

Les personnes infectées par le VIH qui ne présentent aucun signe de la maladie au moment de commencer le traitement, ont-elles un risque plus élevé d’échec du traitement?   Clinical Infectious Disease. Ces dernières années, on conseille aux personnes infectées par le VIH de commencer un traitement le plus rapidement possible après le diagnostic. Cette stratégie […]

Speich et al., Pilot trial comparing mRNA vaccines Comirnaty and mRNA vaccines Moderna in immunocompromised patients

A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®    Trials The ongoing SARS-CoV-2 pandemic has highlighted that new, fast and flexible clinical trial approaches are needed to assess the efficacy and safety of interventions in a timely […]

Mocroft et al., Smoking, current CD4+ cell count, viral load and cancer

The interrelationship of smoking, CD4+ cell count, viral load and cancer in persons living with HIV.   AIDS Mocroft et al. on behalf of the RESPOND study group aimed to investigate whether the impact of smoking on development of cancer is similar for those with different combinations of CD4+ and viral load, reflecting both viral suppression […]

Abela et al., Resistenza ai farmaci antiretrovirali nei pazienti con condizioni sociali difficili nella SHCS

L’insorgenza della resistenza ai farmaci antiretrovirali si osserva nei pazienti con condizioni sociali difficili nella SHCS.    Clinical Infectious Disease Dall’introduzione negli anni 90 della terapia antiretrovirale combinata (cART), il tasso di resistenze acquisite ai medicamenti contro l’HIV è diminuito in modo radicale. Malgrado ciò l’esperienza quotidiana mostra che ci sono ancora persone che vivono […]

Abela et al., Medikamentenresistenzen bei sozial benachteiligten Patienten und Patientinnen in der SHCS

Die Entstehung von Medikamentenresistenzen wird in der SHCS bei sozial benachteiligten Patienten und Patientinnen beobachtet.    Clinical Infectious Disease Seit der Einführung der kombinierten antiretroviralen Therapie (cART) in den 90er Jahren in der Schweiz ist die Rate der erworbenen Arzneimittelresistenzen gegen HIV erfreulicherweise drastisch zurückgegangen. Die Alltagserfahrung zeigt jedoch, dass es weiterhin Menschen gibt, die […]

Abela et al., Résistance aux médicaments observée chez les patients socialement défavorisés de la SHCS

L’émergence de la résistance aux médicaments est observée chez les patients socialement défavorisés de la SHCS.    Clinical Infectious Disease Depuis l’introduction de la thérapie antirétrovirale combinée (cART) en Suisse dans les années 1990, le taux de résistance acquise aux médicaments contre le VIH a heureusement diminué de manière radicale. Cependant, l’expérience quotidienne montre qu’il […]

Nguyen et al., Trans women in the SHCS: A distinct HIV risk group

Identifying and characterizing trans women in the Swiss HIV Cohort Study as an epidemiologically distinct risk group.   Clinical Infectious Disease Nguyen et al. aimed to identify trans women in the Swiss HIV Cohort Study (SHCS) using a variety of sources. Moreover, they aimed to better understand HIV transmission events and to compare demographic, clinical, mental, […]

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