Swiss HIV Cohort Study

Mocroft et al., Hepatitis B virus infection and nonliver malignancies

The association between hepatitis B virus infection and nonliver malignancies in persons living with HIV: results from the EuroSIDA study.    HIV Medicine Mocroft and Miró et al. aimed to determine whether people living with HIV (PLWH) and hepatitis B virus (HBV) in the EuroSIDA study are at increased risk for nonliver cancer compared to […]

Balakrishna et al. Bacterial pneumonia in the SHCS

Decreasing incidence and determinants of bacterial pneumonia in people with HIV: The Swiss HIV Cohort Study.    Journal of Infectious Diseases Balakrishna et al. aimed to estimate the incidence rate of bacterial pneumonia in the Swiss HIV Cohort Study (SHCS) and to assess the risk factors associated with incidence of bacterial pneumonia. The authors included […]

Kowalska et al., Prevalence and outcomes of pregnancies in women with HIV

Prevalence and outcomes of pregnancies in women with HIV over a 20-year period.    AIDS Kowalska et al. evaluated time trends and outcomes of pregnancies among European women with HIV between 1996 and 2015 in the EuroSIDA cohort. Audits were performed annually to collect information on pregnancies in female cohort participants aged between 16 and […]

Scherrer et al., Cohort profile update: The Swiss HIV Cohort Study (SHCS)

Cohort profile update: The Swiss HIV Cohort Study (SHCS).    International Journal of Epidemiology Scherrer et al. aimed to update the Swiss HIV Cohort Study (SHCS) cohort profile, published in 2009, because of changing characteristics of the HIV-infected population in Switzerland and changes in the focus of research within the SHCS. In brief, the SHCS […]

Hovaguimian et al., Rischio a lungo termine di infezione HIV nelle persone che hanno ricevuto una PPE all’HIV

Rischio a lungo termine di infezione HIV nelle persone che hanno ricevuto una profilassi post-esposizione all’HIV.   Nature Communications La profilassi post-esposizione (PEP) è caratterizzata dall’assunzione di tre medicamenti antiretrovirali per evitare la trasmissione dell’HIV dopo un’esposizione, più frequentemente dopo un rapporto sessuale non protetto. Benché la PEP sia una misura ben documentata per prevenire […]

Hovaguimian et al., Langfristiges HIV-Infektionsrisiko bei Personen, die sich einer HIV PEP unterzogen haben

Langfristiges HIV-Infektionsrisiko bei Personen, die sich einer HIV Postexpositionsprophylaxe unterzogen haben.    Nature Communications Die medikamentöse Postexpositionsprophylaxe (PEP) bezeichnet die Einnahme von drei antiretroviralen Medikamenten zur Verhinderung der Übertragung von HIV nach einer Exposition, meistens nach ungeschütztem Geschlechtsverkehr. Obwohl die PEP eine etablierte Massnahme zur Verhinderung der HIV-Infektionen darstellt, sind die Erkenntnisse über das langfristige […]

Hovaguimian et al., Risque à long terme d’infection par le VIH chez les personnes qui ont reçu une PPE au VIH

Risque à long terme d’infection par le VIH chez les personnes qui ont reçu une prophylaxie post-exposition au VIH.    Nature Communications La prophylaxie post-exposition (PPE) désigne la prise de trois médicaments antirétroviraux pour éviter la transmission du VIH après une exposition, le plus souvent après un rapport sexuel non protégé. Bien que la PPE […]

Courlet et al., Pharmacokinetic/pharmacodynamic modelling to describe the cholesterol lowering effect of rosuvastatin in PLWHIV

Pharmacokinetic/pharmacodynamic modelling to describe the cholesterol lowering effect of rosuvastatin in people living with HIV.    Clinical Pharmacokinetics Courlet et al. aimed to characterise the pharmacokinetic profile of rosuvastatin and to describe the relationship between different rosuvastatin concentrations and non-high-density (HDL) cholesterol levels in people living with HIV using model-based simulations. Participants of the Swiss […]

Jakeman et al., Anticholinergic use in elderly PLWH

Anticholinergic medication use in elderly people living with HIV and self-reported neurocognitive impairment: a prospective cohort study.    Journal of Antimicrobial Chemotherapy Jakeman et al. aimed to determine the proportion of patients ≥65 years within the Swiss HIV Cohort Study (SHCS) who receive drugs with anticholinergic (ACH) activity, and evaluated the impact of ACH medication […]

Balakrishna et al., Assessing the drivers of syphilis among MSM in Switzerland

Assessing the drivers of syphilis among men who have sex with men in Switzerland reveals a key impact of screening frequency: A modelling study.    PLoS Computational Biology Balakrishna et al. aimed to identify the drivers of syphilis transmission in MSM in Switzerland between 2006 and 2017 as well as the effect of potential interventions […]