Swiss HIV Cohort Study

Greenberg et al., Clinical outcomes of dual therapy in HIV

Clinical outcomes of two-drug regimens vs. three-drug regimens in antiretroviral treatment-experienced people living with HIV.   Clinical Infectious Diseases. Greenberg et al. on behalf of the RESPOND (International Cohort Consortium of Infectious Diseases) Study Group aimed to compare clinical outcomes with use of 2-drug regimens (2DRs) versus 3-drug regimens (3DRs) in people living with HIV. Antiretroviral […]

Scherrer et al., Cohort profile update SHCS

We are happy to distribute the Cohort profile update that has just been published online in the International Journal of Epidemiology. We want to thank all of you who have helped to put this together and particularly Alexandra Scherrer and Anna Traytel who took on the major part of this work. For future papers, if […]

Duran Ramirez et al., Non-B subtypes among MSM in Switzerland

Increasing frequency and transmission of HIV-1 non-B subtypes among men who have sex with men in the Swiss HIV Cohort Study.    Journal of Infectious Diseases Duran Ramirez and Ballouz et al. assessed temporal trends and transmission dynamics of HIV-1 non-B subtypes – historically transmitted mainly through heterosexual contacts and among individuals of non-European origin […]

Schoepf and Thorball et al., Polygenic risk score CAD HIV

Coronary artery disease–associated and longevity-associated polygenic risk scores for prediction of coronary artery disease events in persons living with human immunodeficiency virus: The Swiss HIV Cohort Study.   Clinical Infectious Disease Schoepf and Thorball et al. evaluated whether polygenic risk scores improve prediction of cardiovascular disease (CAD) events in people living with HIV. In the present […]

Kovari et al., Antiretrovirale Medikamente und Verkalkung der Herzkranzgefässe

Antiretrovirale Medikamente und Verkalkung der Herzkranzgefässe.   Clinical Infectious Disease Verschiedene antiretrovirale Substanzen wurden in Studien mit einer koronaren Herzkrankheit, das heisst einer Verkalkung und Verengung der Herzkranzgefässe und Vorstufe eines Herzinfarktes, in Verbindung gebracht. Die Resultate der in den letzten Jahren durchgeführten Studien waren aber nicht einheitlich. In der hier besprochenen Studie wurde bei […]

Kovari et al., Médicaments antirétroviraux et calcification des artères coronaires

Médicaments antirétroviraux et calcification des artères coronaires.    Clinical Infectious Disease. Diverses substances antirétrovirales ont été associées dans des études à des maladies coronariennes, c’est-à-dire à la calcification et au rétrécissement des artères coronaires, précurseurs d’une crise cardiaque. Cependant, les résultats des études menées ces dernières années sont contradictoires. Dans l’étude présentée ici, une coronarographie […]

Kovari et al., Farmaci antiretrovirali e calcificazioni delle arterie coronarie

Farmaci antiretrovirali e calcificazioni delle arterie coronarie.   Clinical Infectious Disease Diversi farmaci antiretrovirali sono stati associati in studi clinici a malattia coronarica, ossia restringimento e calcificazione della parete delle coronarie che preludono a un infarto miocardico. I risultati degli studi condotti negli ultimi anni danno però risultati contradditori. In questo studio, realizzato nell’ambito dello […]

Darling et al., Alcohol, HIV and neurocognitive function

Alcohol consumption and neurocognitive deficits in people with well-treated HIV in Switzerland.    PLoS ONE Darling et al. examined the association between alcohol consumption and neurocognitive impairment (NCI) among participants of the Neurocognitive Assessment in the Metabolic and Aging Cohort (NAMACO) within the SHCS. Participants had standardized neurocognitive testing performed. Individuals were categorized as having […]

Raffenberg et al., Effet du report du traitement antirétroviral pendant la première phase après l’infection par le VIH sur la longueur des télomères

Effet du report du traitement antirétroviral pendant la première phase après l’infection par le VIH sur la longueur des télomères.    Journal of Infectious Diseases Aujourd’hui, les personnes vivant avec le VIH ont à peu près la même espérance de vie que celles qui ne le sont pas. Cela est principalement dû au développement continu […]

Raffenberg et al., Effetto del ritardo nell’iniziare una terapia antiretrovirale durante la prima fase di un’infezione da HIV sulla lunghezza dei telomeri

Effetto del ritardo nell’iniziare una terapia antiretrovirale durante la prima fase di un’infezione da HIV sulla lunghezza dei telomeri.     Journal of Infectious Diseases Al giorno d’oggi le persone che vivono con l’HIV hanno all’incirca la stessa speranza di vita di coloro che non hanno l’infezione. Ciò è principalmente dovuto al continuo sviluppo di […]