Atkinson et al., HIV viral load and risk of tuberculosis
HIV replication and tuberculosis risk among people living with HIV in Europe: A multicohort analysis, 1983–2015 This study investigated the role of ongoing HIV replication as an independent risk factor for tuberculosis (TB) among individuals living with HIV in Europe. Drawing on data from 25 European cohorts, the researchers analyzed records of 272’548 people who […]
Turk and Labarile et al., long-term immune recovery under ART
Characterization and determinants of long-term immune recovery under suppressive antiretroviral therapy Long-term immune recovery is one of the main treatment goals for people with HIV receiving antiretroviral therapy (ART). While most individuals achieve viral suppression, the extent of immune restoration can vary substantially. In the present study published in JAIDS, Turk and Labarile et al. […]
Rupasinghe et al., INSTI-related changes in BMI and diabetes risk
Integrase strand transfer inhibitor–related changes in body mass index and risk of diabetes: A prospective study from the RESPOND cohort consortium.  Clinical Infectious Diseases Integrase strand transfer inhibitors (INSTIs) are widely used in HIV treatment due to their strong efficacy and tolerability. However, emerging evidence suggests a link between INSTI use, weight gain, and […]
Künzler-Heule et al., Prevent hepatitis C virus reinfection in HIV infected MSM
Exploring group differences in the response to a sexual risk reduction intervention to prevent hepatitis C virus reinfection in HIV-infected MSM: a mixed-methods study. AIDS Care Counseling individuals with HIV after successful treatment of hepatitis C (HCV) coinfection aims to reduce the risk of reinfection. Condomless anal sex, receptive fisting, sexualized drug use, and injection […]
Riebensahm et al., La diminuzione dell’attività fisica e il lungo tempo trascorso seduti sono associati alla steatosi epatica nelle persone affette da HIV
La diminuzione dell’attività fisica e il lungo tempo trascorso seduti sono associati alla steatosi epatica nelle persone affette da HIV. JAIDS L’attività fisica regola l’accumulo di grasso nel fegato e riduce il rischio di steatosi epatica, una malattia in cui il grasso si accumula nel fegato. In questo studio è stata analizzata l’associazione tra attività […]
Riebensahm et al., La diminution de l’activité physique et la position assise prolongée sont associées à la stéatose hépatique chez les personnes vivant avec le VIH
La diminution de l’activité physique et la position assise prolongée sont associées à la stéatose hépatique chez les personnes vivant avec le VIH. JAIDS L’activité physique régule le stockage des graisses dans le foie et réduit le risque de stéatose hépatique, une maladie dans laquelle les graisses s’accumulent dans le foie. Cette étude a examiné […]
Riebensam et al., Verminderte körperliche Aktivität und langes Sitzen stehen im Zusammenhang mit Fettleber bei Menschen mit HIV
Verminderte körperliche Aktivität und langes Sitzen stehen im Zusammenhang mit Fettleber bei Menschen mit HIV. JAIDS Körperliche Aktivität reguliert die Fettspeicherung in der Leber und verringert das Risiko für eine Fettleber, eine Erkrankung, bei der sich Fett in der Leber ansammelt. In dieser Studie wurde der Zusammenhang zwischen körperlicher Aktivität und einer Fettleber in der […]
Schwarzmueller et al., Decoupling HIV-1 ARV inhibition from plasma antibody activity
Decoupling HIV-1 antiretroviral drug inhibition from plasma antibody activity to evaluate broadly neutralizing antibody therapeutics and vaccines. Cell Reports Medicine On behalf of the Swiss HIV Cohort Study (SHCS), Schwarzmüller et al. developed and validated ART-DEX, a novel high-throughput method to separate antiretroviral drugs (ARVs) from plasma of people with HIV (PWH). This method enables […]
Johansen et al., Risk of TB after initiation of ART among PWHIV
Risk of tuberculosis after initiation of antiretroviral therapy among persons with HIV in Europe.  International Journal of Infectious Diseases. On behalf of the RESPOND consortium, Johansen et al. aimed to quantify the risk of tuberculosis (TB) over time and associated risk factors in persons with HIV initiating antiretroviral therapy (ART). They included individuals enrolled in […]
Neuner-Jehle et al., Genome-wide screen for HIV-1 variants under HLA-dependent selection
Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen. PLoS Pathogens HIV constantly evolves to escape the human immune system, particularly through interactions with the human leukocyte antigen (HLA) system, which helps the body recognize and fight infections. Neuner-Jehle et al. developed a new method to systematically identify […]