Swiss HIV Cohort Study

Zhang et al., New findings on HIV reservoirs highlight importance of early treatment

HIV-1 diversity in viral reservoirs obtained from circulating T-cell subsets during early ART and beyond.   PLoS Pathogens Individuals living with HIV carry persistent virus reservoirs that can remain hidden even during effective antiretroviral therapy (ART). These reservoirs can potentially reactivate, leading to renewed infection. In a recent study published in PLOS Pathogens, Zhang et […]

Hutchinson et al., Clinical characteristics of women with HIV in the RESPOND cohort

Clinical characteristics of women with HIV in the RESPOND cohort: A descriptive analysis and comparison to men. HIV Medicine Women with HIV remain underrepresented in clinical research, yet understanding sex and gender differences is crucial to addressing their unique needs, particularly as the population ages and comorbidities become more prevalent. In a study published in […]

Tepekule et al., Transcriptional profile of MTB infection in PWH

Transcriptional profile of Mycobacterium tuberculosis infection in people living with HIV.   iScience Tepekule et al. investigated whether changes in the immune system induced by Mycobacterium tuberculosis (MTB), as predicted from epidemiological observations, can be detected in peripheral blood in people with HIV (PWH). The authors hypothesized that exposure to MTB does not only induce […]

Weber et al., Evoluzione nel tempo delle cause di decesso delle persone che vivono con HIV: analisi dei dati dello Studio svizzero della coorte HIV

Evoluzione nel tempo delle cause di decesso delle persone che vivono con HIV: analisi dei dati dello Studio svizzero della coorte HIV.   Clinical Infectious Diseases Grazie ai notevoli progressi nella terapia antiretrovirale, il numero di decessi legati all’HIV/AIDS in Svizzera è diminuito in modo significativo. Tuttavia, le altre cause di morte, come le malattie […]

Weber et al., Changements des causes de décès au fil du temps: analyse de l’Etude suisse de cohorte VIH

Changements des causes de décès au fil du temps: analyse de l’Etude suisse de cohorte VIH.  Clinical Infectious Diseases Les avancées majeures dans le traitement de l’infection par le VIH grâce à la thérapie antirétrovirale ont permis de réduire de manière significative le nombre de décès liés au SIDA en Suisse. Cependant, les autres causes […]

Weber et al., Veränderungen der Todesursachen über die Zeit: Analyse der SHCS

Veränderungen der Todesursachen über die Zeit: Analyse der Schweizer HIV Kohortenstudie. Clinical Infectious Diseases Die grossen Fortschritte in der Behandlung der HIV Infektion mit Hilfe der antiretroviralen Therapie haben dazu beigetragen, die AIDS-bedingte Sterberate in der Schweiz drastisch zu reduzieren. Weniger gut erforscht sind jedoch Veränderungen von anderen Todesursachen über die Zeit, wie etwa leberbedingte […]

Trickey et al., Care interruptions and mortality among adults in Europe and North America

Care interruptions and mortality among adults in Europe and North America: a collaborative analysis of cohort studies.  AIDS For people with HIV, continuous antiretroviral therapy (ART) has dramatically reduced HIV-related illness and death. However, interruptions in HIV care and treatment remain a significant challenge. In a comprehensive study published in AIDS, Trickey et al. examined […]

Zeeb et al., Self-reported neurocognitive complaints in the SHCS

Self-reported neurocognitive complaints in the Swiss HIV Cohort Study – a viral genome wide association study.   Brain Communications People with HIV (PWH) may experience neurocognitive complaints which can significantly impact their quality of life. While these complaints are often multifactorial, the role of the HIV genome in their development has remained unclear. In a […]

Avery et al., Numero di leucociti nel sangue e rischio di eventi cardiovascolari

Numero di leucociti nel sangue e rischio di eventi cardiovascolari: un’analisi longitudinale nei partecipanti allo Studio Svizzero della Coorte HIV.   Clinical Infectious Disease Le persone che vivono con HIV (PVHIV) sono a rischio più elevato della popolazione generale di presentare un evento cardiovascolare. Questo rischio è legato ai classici fattori di rischio (tabagismo, sedentarietà, colesterolo […]

Avery et al., Taux de leucocytes et risque d’évènements cardiovasculaires

Taux de leucocytes et risque d’évènements cardiovasculaires: une analyse longitudinale chez les participants de l’Etude suisse de cohorte VIH.   Clinical Infectious Disease Les personnes vivant avec le VIH sont plus à risque de présenter un événement cardiovasculaire par rapport à la population générale. Ce risque est lié notamment à la présence de facteurs de […]