Salazar-Vizcaya et al., Anstieg der in der Schweiz erworbenen HCV Neuinfektionen bei MSM
Anstieg der in der Schweiz erworbenen Hepatitis C Neuinfektionen bei HIV-positiven Männern, die Sex mit Männer haben, aus der Schweizerischen HIV Kohortenstudie.   Journal of Infectious Disease Die niederschwellige Verfügbarkeit der neuen hochwirksamen Hepatitis C (HCV) Medikamente in der Schweiz und die Behandlung der Personen mit einer erfassten HCV Infektion hat die Rate an HCV Neuinfektionen […]
Salazar-Vizcaya et al., Augmentation des nouvelles infections VHC acquises en Suisse chez les HSH
Augmentation des nouvelles infections hépatite C acquises en Suisse chez les hommes qui ont des rapports sexuels avec des hommes et qui participent à l’Etude suisse de cohorte VIH.  Journal of Infectious Disease Le nombre des nouvelles infections avec le virus de l’hépatite C (VHC) chez les hommes VIH-positifs qui ont des rapports sexuels […]
Salazar-Vizcaya et al., Aumento delle nuove infezioni HCV acquisite in Svizzera negli MSM
Aumento delle nuove infezioni da virus dell’epatite C acquisite in Svizzera negli uomini che hanno rapporti sessuali con altri uomini e che partecipano allo studio svizzero della coorte HIV (SHCS).  Journal of Infectious Disease Il Svizzera il numero di nuove infezioni da virus dell’epatite C (HCV) negli uomini HIV positivi che hanno rapporti sessuali con […]
Kusejko et al., Interaction of HIV-1 with comorbidities
A systematic phylogenetic approach to study the interaction of HIV-1 with coinfections, non-communicable and opportunistic diseases. Â Â Journal of Infectious Disease Kusejko et al. aimed to systematically test whether coinfections spread along the HIV-1 transmission network and whether similarities in HIV-1 genomes predict AIDS-defining illnesses and comorbidities. A maximum-likelihood phylogenetic tree was built using sequences […]
Salazar-Vizcaya et al., International versus local HCV transmission
Changing trends in international versus domestic HCV transmission in HIV-positive MSM: A perspective for the DAA scale-up era. Â Â Journal of Infectious Disease Salazar-Vizcaya et al. aimed to classify hepatitis C virus (HCV) infections in HIV-positive men who have sex with men (MSM) in Switzerland as domestically or internationally acquired, and to estimate how this […]
Abela et al., Auftreten einer erworbenen Resistenz auf HIV-Medikamente in der SHCS
Auftreten einer erworbenen Resistenz auf HIV-Medikamente in der Schweizerischen HIV Kohortenstudie.   Clinical Infectious Disease Glücklicherweise ist die Rate an erworbener Resistenz auf HIV-Medikamente aufgrund der heutzutage sehr potenten HIV-Medikamente stark zurückgegangen. Die vorliegende Arbeit hat Faktoren ermittelt, welche mit einem erhöhten Risiko für eine erworbene Resistenz vergesellschaftet sind: Arbeitslosigkeit, Afrikanische Herkunft, Symptome einer psychiatrischen […]
Abela et al., Apparition d’une résistance acquise aux médicaments anti-VIH dans l’Etude suisse de cohorte VIH
Apparition d’une résistance acquise aux médicaments anti-VIH dans l’Etude suisse de cohorte VIH.   Clinical Infectious Disease Le nombre de résistances acquises aux médicaments anti-VIH a heureusement fortement diminué grâce aux médicaments anti-VIH hautement efficaces. Cette étude a identifié les facteurs qui augmentent le risque d’acquérir une résistance aux traitements: chômage, origine africaine, symptômes d’une maladie […]
Wymant et al., Reconstruction of whole HIV genomes from short-read sequence
Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with SHIVER.  Virus Evolution Studying the evolution of viruses and their molecular epidemiology relies on accurate viral sequence data, so that small differences between similar viruses can be meaningfully interpreted. Despite its higher throughput and more detailed minority variant data, next-generation sequencing has […]
Abela et al., Apparizione di resistenze acquisite ai medicamenti anti-HIV nello studio svizzero della coorte HIV
Apparizione di resistenze acquisite ai medicamenti anti-HIV nello studio svizzero della coorte HIV.  Clinical Infectious Disease Il numero di resistenze acquisite ai medicamenti anti-HIV è in forte diminuzione grazie ai medicamenti antiretrovirali altamente efficaci. Questo studio ha identificato i fattori che aumentano il rischio di acquisire una resistenza ai trattamenti: disoccupazione, origine africana, sintomi […]
Wymant et al., Inferring transmission from within- and between-host pathogen genetic diversity
PHYLOSCANNER: Inferring Transmission from Within- and Between-Host Pathogen Genetic Diversity. Â Molecular Biology and Evolution A central feature of pathogen genomics is that different infectious particles (virions and bacterial cells) within an infected individual may be genetically distinct, with patterns of relatedness among infectious particles being the result of both within-host evolution and transmission from […]