Swiss HIV Cohort Study

Livio et al., Inappropriate prescribing in elderly people living with HIV

Analysis of inappropriate prescribing in elderly patients of the Swiss HIV Cohort Study reveals gender inequity. Journal of Antimicrobial Chemotherapy Livio et al. aimed to determine the prevalence of and risk factors for inappropriate prescribing in geriatric medicine among individuals aged ≥75 years enrolled in the Swiss HIV Cohort Study. The authors did a retrospective […]

Dietrich et al., Kidney dysfunction and HIV

Rapid progression of Kidney dysfunction in Swiss people living with HIV: Contribution of polygenic risk score and D:A:D clinical risk score.    Journal of Infectious Diseases Dietrich et al. aimed to assess and quantify the contribution of genetic background, D:A:D chronic kidney disease (CKD) risk score, and relevant antiretroviral therapy (ART) exposures to rapid progression of […]

Kusejko et al., Interaction complexe entre l’infection de la tuberculose et le VIH

Interaction complexe entre l’infection de la tuberculose et le VIH.    PLoS Biology Si les gens souffrent de plusieurs maladies infectieuses, celles-ci interagissent toujours les unes avec les autres. C’est également le cas chez des patients atteints du VIH: s’ils sont également infectés par la tuberculose, ils sont mieux à même de contrôler le virus […]

Kusejko et al., Interazione complessa tra tubercolosi e HIV

Interazione complessa tra tubercolosi e HIV.    PLoS Biology In caso di multiple malattie infettive concomitanti ci sono sempre interazioni tra le une e le altre. Ciò accade anche nelle persone con infezione HIV: se sussiste un’infezione concomitante con Mycobacterium tuberculosis (MTB), l’agente della tubercolosi, i pazienti sono in grado di controllare meglio l’HIV e […]

Kusejko et al., Komplexe Interaktion zwischen Tuberkulose-Infektion und HIV

Komplexe Interaktion zwischen Tuberkulose-Infektion und HIV.    PLoS Biology Leiden Menschen an mehreren Infektionskrankheiten, haben diese untereinander immer eine Wechselwirkung. So auch bei HIV-Patientinnen und Patienten: Sind sie zusätzlich mit Tuberkulose infiziert, können sie das HI-Virus besser kontrollieren und es treten seltener opportunistische Infektionen auf. Das haben Forschende aus der Schweizerischen HIV Kohortenstudie (SHCS) in […]

Gryaznov et al., Smartphone app and CO self-monitoring support for smoking cessation

Smartphone app and carbon monoxide self-monitoring support for smoking cessation: A randomised controlled trial nested into the Swiss HIV Cohort Study.   JAIDS Gryaznov et al. investigated whether exhaled carbon monoxide (CO) self-monitoring in conjunction with a smoking cessation app may improve smoking cessation in HIV-positive smokers. They nested a randomized controlled into the Swiss […]

Reichmuth et al., HIV-1 transmission drivers

Using longitudinally sampled viral nucleotide sequences to characterize the drivers of HIV-1 transmission.   HIV Medicine Reichmuth et al. aimed to develop and to test a molecular epidemiology method based on phylogeny reconstruction and cluster analysis to characterize potential HIV-1 transmitters and understand the drivers of the HIV-1 epidemic in Switzerland. This method was developed and […]

Mocroft et al., Outcomes in antiretroviral-naïve adults

Treatment outcomes of integrase inhibitors, boosted protease inhibitors and non-nucleoside reverse transcriptase inhibitors in antiretroviral naïve persons starting treatment.   HIV Medicine Mocroft et al. on behalf of the RESPOND study-group aimed to compare shorter term virological and immunological outcomes and clinical events of AIDS/death in ART-naïve persons starting antiretroviral therapy (ART) in RESPOND with […]

Kusejko et al., The interplay of HIV and latent tuberculosis

Diagnosis of latent tuberculosis infection is associated with reduced HIV viral load and lower risk for opportunistic infections in people living with HIV.     PLoS Biology Kusejko et al. aimed to investigate the association of Mycobacterium tuberculosis (MTB) status with HIV disease progression, including both the HIV set point viral load (SPVL) and the […]

Pyngottu et al., Treatment failure on integrase inhibitor

Predictors of virological failure and time to viral suppression of first line integrase inhibitor based antiretroviral treatment.   Clinical Infectious Diseases Pyngottu et al. aimed to identify risk factors for treatment failure of integrase strand transfer inhibitor (InSTI-) based combined antiretroviral treatment (cART) in drug-naive individuals living with HIV from the Swiss HIV Cohort Study […]