Neesgard et al., Associations between INSTI and CVD in people living with HIV
Associations between integrase strand-transfer inhibitors and cardiovascular disease in people living with HIV: a multicentre prospective study from the RESPOND cohort consortium. Lancet HIV Neesgard et al. investigated whether integrase strand-transfer inhibitors (INSTI) are associated with an increased risk for cardiovascular disease among people living with HIV in the International Cohort Consortium of Infectious Disease […]
Kusejko et al., HCVree post screening
Sustained effect on hepatitis C elimination among men who have sex with men in the Swiss HIV Cohort Study: A systematic re-screening for hepatitis C RNA two years following a nation-wide elimination program. Clinical Infectious Diseases Kuseijo et al. aimed to explore the long-term effect of the Swiss HCVree Trial. This trial was conducted in […]
Branca et al., HIV-1 reservoir and dual therapy
Role of the HIV-1 reservoir to maintain viral suppression in a simplified strategy for the long-term management of HIV-1 infection (The SIMPL’HIV Trial). Frontiers in Virology Branca et al. assessed the association between the size of the HIV reservoir and the maintenance of HIV viral suppression among participants of the SIMPL’HIV Trial. The SIMPL’HIV […]
Nguyen et al., Les femmes transgenres dans la SHCS: description d’un groupe de transmission du VIH à part entière
Les femmes transgenres dans la SHCS: description d’un groupe de transmission du VIH à part entière. Clinical Infectious Disease Le terme “trans” est souvent utilisé pour désigner des personnes qui ne s’identifient pas au sexe qui leur a été attribué à la naissance. Il peut s’agir de personnes qui ont subi des opérations de réassignation […]
Friedrich et al., Conformations of the HIV-1 V3 loop crown are targetable for broad neutralization
Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nature Communications The V3 loop of the HIV-1 envelope (Env) protein elicits a vigorous, but largely non-neutralizing antibody response directed to the V3-crown, whereas rare broadly neutralizing antibodies (bnAbs) target the V3-base. In this work, Friedrich et al. used the Designed […]
Nguyen et al., Le donne transessuali nella SHCS: descrizione della trasmissione HIV in un gruppo specifico
Le donne transessuali nella SHCS: descrizione della trasmissione HIV in un gruppo specifico. Clinical Infectious Disease Il termine “trans” è frequentemente utilizzato per definire delle persone che non si identificano con il sesso attribuito loro alla nascita. Si tratta di persone che sono state sottoposte a operazioni di ri-orientamento sessuale, a terapie ormonali o che […]
Nguyen et al., Transfrauen in der SHCS: Beschreibung einer eigenständigen HIV-Übertragungsgruppe
Transfrauen in der SHCS: Beschreibung einer eigenständigen HIV-Übertragungsgruppe. Clinical Infectious Disease Der Begriff «trans» wird oftmals für Personen verwendet, welche sich nicht mit dem bei der Geburt zugeordneten Geschlecht identifizieren. Dies können Menschen sein, welche geschlechtsangleichende Operationen oder Hormontherapien durchführen liessen, oder die sonst im sozialen Leben mit einem anderen Geschlecht auftreten. Neben «trans» […]
Salazar-Vizcaya et al., Interaction between behavioral and transmission clusters
An approach to quantifying the interaction between behavioral and transmission clusters. Viruses Groups of individuals with similar sexual risk behavior have been identified previously in people living with HIV and incident hepatitis C virus (HCV) infection. In addition, phylogenetic analyses have confirmed the presence of HCV transmission networks. However, little is known about the interplay […]
Seifert et al., Detecting selection in the HIV-1 genome during sexual transmission events
Detecting selection in the HIV-1 genome during sexual transmission events. Viruses Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive or negative selection during transmission is challenging, because very few virus particles are typically transmitted, and random genetic drift can […]
Gilles et al., Volonté des personnes vivant avec le VIH en Suisse à participer à des essais de guérison du VIH
Volonté des personnes vivant avec le VIH en Suisse à participer à des essais de guérison du VIH. JAIDS Les récents progrès réalisés dans les thérapies cellulaires et géniques contre le cancer suggèrent qu’elles représentent des stratégies plausibles pour guérir le VIH. Cependant, les risques et contraintes associés à ces thérapies nécessitent une compréhension […]