Hamusonde et al., Triggers of change in sexual behavior among people with HIV
Triggers of change in sexual behavior among people with HIV: The Swiss U = U statement and Covid-19 compared. Journal of Infectious Diseases Hamusonde et al. aimed to investigate the impact of 2 external factors (termed “triggers” herein) which might influence sexual behavior: (1) the Swiss U = U statement (“trigger of relief”), and […]
Jaschinski et al., Recent abacavir use and incident CVD in contemporary treated people living with HIV
Recent abacavir use and incident cardiovascular disease in contemporary treated people living with HIV. AIDS Jaschinski et al. analyzed the relationship between abacavir (ABC) use and the development of cardiovascular disease (CVD) events among participants of RESPOND, a large collaboration of HIV cohorts from Europe and Australia. All individuals with follow-up after 2012 were included. […]
Pyngottu et al., Faktoren, welche ein Therapieversagen bei Integrase-basierten Erstlinientherapie vorhersagen
Faktoren, welche ein Therapieversagen bei Integrase-basierten Erstlinientherapie vorhersagen. Clinical Infectious Diseases Integrasehemmer sind seit ein paar Jahren fester Bestandteil der antiretroviralen Therapie, insbesondere auch bei Erstlinientherapie (erste Therapie, die eine Person, die mit HIV lebt, bekommt.) Die Gründe dafür sind einerseits die sehr gute antivirale Wirksamkeit, die gute Verträglichkeit und die, im Vergleich zu […]
Pyngottu et al., Facteurs prédictifs d’échec de traitement de première ligne à base d’inhibiteur de l’intégrase
Facteurs prédictifs d’échec de traitement de première ligne à base d’inhibiteur de l’intégrase. Clinical Infectious Diseases Depuis quelques années, les inhibiteurs de l’intégrase (dolutegravir, bictegravir …) font partie intégrante du traitement antirétroviral, en particulier dans le cadre du traitement de première ligne (premier traitement administré à une personne vivant avec le VIH). Les raisons […]
Pyngottu et al., Fattori predittivi del fallimento di terapie di prima linea con inibitori dell’integrasi
Fattori predittivi del fallimento di terapie di prima linea con inibitori dell’integrasi. Clinical Infectious Diseases Erstautor et al. Da qualche anno, gli inibitori dell’integrasi (dolutegravir, bictegravir, ecc.) sono parte integrante dei trattamenti antiretrovirali, in particolare come componenti dei trattamenti di prima linea (ossia primo trattamento prescritto a una persona che vive con HIV). Si tratta […]
Chaudron et al., HIV-1 superinfection screen in the SHCS
A systematic molecular epidemiology screen reveals numerous HIV-1 superinfections in the Swiss HIV Cohort Study. Journal of Infectious Diseases Chaudron et al. aimed to study immunodeficiency virus type 1 (HIV-1) superinfection in the Swiss HIV Cohort Study (SHCS). Superinfection is the acquisition of another HIV-1 strain among individuals with an already established HIV-1 infection. […]
Hofmann et al., HBV replication during tenofovir therapy
Hepatitis B virus replication during tenofovir therapy is frequent in HIV/HBV coinfection. Clinical Infectious Diseases Hofmann et al. analyzed rates of hepatitis B virus (HBV) suppression with tenofovir-containing antiretroviral therapy (ART), and assessed determinants for ongoing HBV replication despite treatment among people living with HIV and HBV in the Swiss HIV Cohort Study (SHCS). […]
Isfordink et al., DAAs in people with HIV/HCV from sub-Saharan Africa or Southeastern Asia
Low risk of failing direct-acting antivirals in people with HIV/HCV from Sub-Saharan Africa or Southeastern Asia: a European cross-sectional study. Open Forum Infectious Diseases Isfordink et al. for EuroSIDA, the Swiss HIV Cohort Study, and the ATHENA Observational Cohort aimed to investigate the real-world efficacy of direct-acting antivirals (DAA) treatment in individuals with HIV/hepatitis […]
Andresen et al., Machine learning predicts STIs in MSM
Unsupervised machine learning predicts future sexual behaviour and sexually transmitted infections among HIV-positive men who have sex with men. PLoS Computational Biology Machine learning is increasingly introduced into medical fields, yet there is limited evidence for its benefit over more commonly used statistical methods in epidemiological studies. In the current study, Andresen et al. designed […]
Chammartin et al., HIV immunology and heart diseases
CD4:CD8 ratio and CD8 cell count and their prognostic relevance for coronary heart disease events and stroke in antiretroviral treated individuals. JAIDS Chammartin et al. investigated whether markers of chronic immune activation play a role in the development of myocardial infarction (MI) or stroke among participants from the Swiss HIV Cohort Study receiving antiretroviral […]