Impact of low-level viremia on clinical and virological outcomes in treated HIV-1-infected patients. AIDS

The Antiretrovira Therapy Cohort Collaboration et al. assessed the prognostic impact of low-level viremia (LVV) among patients receiving antiretroviral therapy. They found that LVV between 200 and 400 copies/ml was significantly associated with virological failure, but not with AIDS event or death. In contrast, LVV between 50-199 copies/ml did not influence the outcome.

This study supports current guidelines defining virological failure as viral load above 200 copies/ml.

PubMed