Swiss HIV Cohort Study

Deutschmann et al., Drug–drug interactions in the era of integrase inhibitors

Prevalence of potential drug-drug interactions in patients of the Swiss HIV Cohort Study in the era of HIV integrase inhibitors.   Clinical Infectious Diseases Deutschmann et al. aimed to assess the prevalence of and risk factors for potential drug–drug interactions (PDDIs) between antiretroviral drugs (ARVs) and co-medications in the SHCS for 2018 and to compare the […]

Braun et al., HCV micro-elimination among HIV+ MSM

A treatment as prevention trial to eliminate hepatitis C among men who have sex with men living with HIV in the Swiss HIV Cohort Study.   Clinical Infectious Disease. Braun et al. aimed to test whether the world health organization (WHO) hepatitis C virus (HCV) elimination targets are achievable in clinical practice among men who […]

Atkinson et al., PcP prophylaxis stop using HIV-RNA

Withholding primary PcP prophylaxis in virologically suppressed HIV patients: An emulation of a pragmatic trial in COHERE.  Clinical Infectious Disease Atkinson et al. for the Opportunistic Infections Project Working Group of the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord investigated whether primary prophylaxis for pneumocystis pneumonia (PcP) might be withheld in all […]

Trickey et al., Survival after diagnosis of cancer among HIV-positive patients

Cause-specific mortality after diagnosis of cancer among HIV-positive patients: A Collaborative analysis of cohort studies.   International Journal of Cancer Trickey et al. on behalf of COHERE in EuroCoord aimed to investigate causes of death within 5 years of cancer diagnosis in people living with HIV (PLHIV) enrolled in European and North American HIV cohorts […]

Combes et al., Antibodies against HPV16E6 oncoprotein to predict anal cancer risk

Antibodies against HPV16E6 oncoprotein in the Swiss HIV Cohort Study: kinetics and anal cancer risk prediction.   International Journal of Cancer Combes et al. aimed to describe human papilloma virus (HPV-) 16E6 antibody kinetics prior to anal cancer in people living with HIV/AIDS (PLWHA) and evaluate the possible contribution of HPV16E6 serology to anal cancer […]

Hersberger et al., SNPs of SOCS-1 associated with HIV progression rate

Polymorphisms of SOCS-1 are associated with rapid HIV progression rate.   Journal of Acquired Immune Deficiency Syndromes Hersberger et al. aimed to investigate the role of 9 single-nucleotide polymorphisms (SNPs) within suppressor of cytokine signaling (SOCS) genes for their association with an HIV progression rate in a cohort of 318 rapid vs 376 slow progressors from […]

European guidelines for the treatment of HIV and COVID-19

Die Europäischen Richtlinien zur Behandlung von HIV äussern sich zur aktuellen Situation bezüglich COVID-19 und Menschen mit HIV. EACS Society COVID and HIV 2020 Zusammenfassend wird auf folgende Punkte hingewiesen: Insgesamt besteht keine klare Evidenz für eine erhöhte Infektionsrate mit COVID-19 oder für häufigere Komplikationen bei Menschen mit HIV. Komorbiditäten, die zu einem schwereren Verlauf […]

Barcelo et al., BMI and WHR change after ART initiation

Impact of genetic and nongenetic factors on body mass index and waist-hip ratio change in HIV-infected individuals initiating antiretroviral therapy.    Open Forum of Infectious Diseases Barcelo et al. aimed to investigate the impact of genetic and nongenetic factors on body mass index (BMI) and waist-hip ratio (WHR) change in HIV-infected individuals initiating antiretroviral therapy. […]

Bachmann et al., Identifying drivers of HIV transmission

Phylogenetic cluster analysis identifies virological and behavioral drivers of HIV transmission in MSM.    Clinical Infectious Diseases. Bachmann et al. aimed to investigate the impacts of treatment as prevention (TasP) and the potentially increased risk behavior on HIV transmission in men who have sex with men (MSM) at both the individual and population levels. Using […]

Metral et al., Neurocognitive assessment in the Metabolic and Aging Cohort (NAMACO)

The Neurocognitive Assessment in the Metabolic and Aging Cohort (NAMACO) study: baseline participant profile.    HIV Medicine Metral et al. for the NAMACO study group aimed to examine baseline neurocognitive impairment (NCI) prevalence and factors associated with NCI among patients enrolled in the Neurocognitive Assessment in the Metabolic and Aging Cohort (NAMACO) study. In brief, the NAMACO […]